Tautomerism is our major research in various aspects:
- from fundamental investigations of the environmental and structural effects to useful practical applications;
- from molecular machinery, switching and sensing systems to drug design;
- from theoretical modeling to real molecules and their experimental investigation.
News
Proton Cranes ─ Tautomeric Systems for Intramolecular Cargo Delivery
Nature effectively employs the light-induced transfer of a proton for rapid interconversion between different electronic [...]
Tautomerism in 1-Pyridin-2-yl-1H-pyrazol-5-ols through the Prism of Molecular Switching: The Rare Case of OH/CH Switching upon Acidic Input
The tautomeric behavior of 1-(2-pyridinyl)-1H-pyrazol-5-ols has been investigated in solution using UV–vis and NMR spectroscopies [...]
Reversible Switching Based on Truly Intramolecular Long-Range Proton Transfer─Turning the Theoretical Concept into Experimental Reality
Herein, we demonstrate a working prototype of a conjugated proton crane, a reversible tautomeric switching [...]