Proton Cranes ─ Tautomeric Systems for Intramolecular Cargo Delivery
Nature effectively employs the light-induced transfer of a proton for rapid interconversion between different electronic [...]
Read MoreTautomerism in 1-Pyridin-2-yl-1H-pyrazol-5-ols through the Prism of Molecular Switching: The Rare Case of OH/CH Switching upon Acidic Input
The tautomeric behavior of 1-(2-pyridinyl)-1H-pyrazol-5-ols has been investigated in solution using UV–vis and NMR spectroscopies [...]
Read MoreReversible Switching Based on Truly Intramolecular Long-Range Proton Transfer─Turning the Theoretical Concept into Experimental Reality
Herein, we demonstrate a working prototype of a conjugated proton crane, a reversible tautomeric switching [...]
Read MoreFavipiravir vs. Deferiprone: tautomeric, photophysical, in vitro biological studies, and binding interactions with SARS-Cov-2-MPro/ACE2
Coronavirus disease 2019 (COVID-19) still remains the most disastrous infection continuously affecting millions of people [...]
Read MoreNeurotensin(8–13) analogs as dual NTS1 and NTS2 receptor ligands with enhanced effects on a mouse model of Parkinson’s disease
The modulatory interactions between neurotensin (NT) and the dopaminergic neurotransmitter system in the brain suggest [...]
Read MoreFavipiravir – Tautomeric and Complexation Properties in Solution
The tautomeric properties of favipiravir, a promising anti-COVID-19 drug, were investigated experimentally for the first [...]
Read MoreLong-Range Proton Transfer in 7-Hydroxy-Quinoline-Based Azomethine Dyes: A Hidden Reason for the Low Efficiency
In the tautomeric Schiff bases, derived from 7-hydroxyquinoline, two competitive channels are possible upon excitation [...]
Read MoreThe progress in the non-destructive analysis and biophotonics was presented at The Sofia Science Festival
The twelfth edition of the Sofia Science Festival was held on October 8 and 9, [...]
Read MoreSolvent-Triggered Long-Range Proton Transport in 7-Hydroxyquinoline Using a Sulfonamide Transporter Group
The ability of long-range proton transport by substitution of 7-hydroxyquinoline at the eighth position with [...]
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